Expression of antioxidant enzymes in lesions of multiple sclerosis and its models
Abstract Oxidative stress promotes tissue injury in the central nervous system in neurological disorders such as multiple sclerosis (MS).To protect against this, antioxidant enzymes including superoxide dismutase-1 (SOD1), heme oxygenase-1 (HO-1), peroxiredoxin-5 (PRDX5) and glutathione peroxidase-4 (GPX4) may be upregulated.However, whether antiox